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These include the augmented expression of myofibroblast differentiation markers, such as SMA and -actin, in response to increased levels of HIF-1 and HIF-2 in human normal fibroblasts exposed to hypoxic conditions and in lung tissue from IPF patients [284]

When the CAG triplet of Htt is repeated more than 35 times, the mutant Huntingtin(mHtt) containing an abnormally long polyQ chain is produced

51 As GSH is known to be present in CSF at very low concentrations (~0.2 mol/l in both healthy and PD subjects), 52 relative to brain tissue concentrations (~1 mmol/l), 7 LCModel-calculated Cr concentrations ( C measured ) were corrected ( C corrected ) using the following formula, which assumes negligible contribution of CSF GSH to the total GSH signal: Absolute GSH levels (IU) were calculated by multiplying GSH/Cr ratios by CSF-corrected absolute Cr concentrations (IU)

MAOA Rs1137070 and Heroin Addiction Interactively Alter Gray Matter Volume of the Salience Network. Scientific Reports, vol

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Cys 2 ), cystine-free (Cys 2 -free), or cystine-free/GSH-supplemented (750 M) medium for the indicated timepoints, and cell numbers were determined (n = 2 technical replicates representative of one experiment)